Dr. H. James Harmon

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EDUCATION

1975-1977 Postdoctoral Research with Prof. Britton Chance, Johnson Research Foundation, University of Pennsylvania, Philadelphia PA
1974-1975 Postdoctoral Research with Dr. C.P. Lee, Johnson Research Foundation, University of Pennsylvania, Philadelphia, PA
1974 Ph.D. Biology, Purdue University, West Lafayette. IN. Advisor, Professor F. L. Crane
1971 M.S. Cell Biology, Purdue University, West Lafayette, IN
1968 B.S. Biology, Purdue University, West Lafayette, IN

 

 

ADMINISTRATIVE EXPERIENCE

1995-1997 Coordinator of Intellectual Property and Research Compliance. Function as technology transfer officer as well as coordinator of government compliance issues (Human subjects, animal research, radiation safety, Institutional Biosafety Committee (DNA, clones, cell lines, etc), biohazards, and other compliance issues that affect research.
1992-1995 Coordinator of Intellectual Properties for Oklahoma State University (serving as patent/copyright officer, director of technology transfer, etc.)
  I also served as the official in charge of implementing and adjudicating the Conflict of Interest policy.
  I also represented OSU at the meetings of the Council on Governmental Relations (COGR) in Washington, DC.

 

 

SPECIAL TRAINING AND PREVIOUS POSITIONS

2000 - Oklahoma State University
Professor of Physics, Department of Physics
Center for Sensors and Sensor Technology
1993 - 2000 Department of Microbiology
Professor of Physics
Coordinator, Intellectual Properties
Oklahoma State University
1992 - 1993 Professor, Oklahoma State University
Department of Microbiology
Adjunct Professor of Physics
Coordinator, Intellectual Properties
Oklahoma State University
1990 - 1992 Professor, Oklahoma State University
Department of Microbiology
Adjunct Professor of Physics
1988 - 1990 Professor, Oklahoma State University
Joint Appointment in Physics and Zoology
1983 - 1988 Associate Professor, Oklahoma State University
Joint Appointment in Physics and Zoology
1977 - 1983 Assistant Professor, Undergraduate Physics 1014, 1114 1214; Cell and Molecular Biology course BISC 3013, 3014; Graduate course on Membrane Biophysics and Bioenergetics, PHYS/BISC 5353; Undergraduate Introductory Biology course BISC 1214; Biophysics, PHYS/BISC 4313.
1969 - 1972 Instructor, Principles of Biology Laboratories, 100% time. Purdue University.

 

 

AREAS OF CURRENT TEACHING COMPETENCE

  • Biophysics
  • Cell & Molecular Biology
  • Cytology
  • Introductory Biology
  • Introductory Physics
  • Bioenergetics
  • Membrane Biophysics/Bioenergetics
  • "Physics for Poets"

 

 

MEMBERSHIPS

  • American Chemical Society
  • American Physical Society
  • Sigma Xi
  • National Defense Industry Association
  • Society of Porphyrins and Phthalocyanines
  • American Society for Biochemistry and Molecular Biology
  • American Assoc. for Adv. of Science

 

 

PROFESSIONAL ACTIVITIES

1993 - 1996 Executive Committee, Bioenergetics Subgroup, Biophysical Society.
1989 - 1995 Appointed by Gov. Henry Bellmon to Oklahoma Health Research Committee of Oklahoma Center for Advancement of Science and Technology (OCAST).
1982 Chairman, Biochemistry Biophysics Section, Oklahoma Academy of Science.
1981 Vice Chairman, Biochemistry Biophysics Section, Oklahoma Academy of Science.
1981 - 1983 Chaired Biochemistry Biophysics Section, Oklahoma Academy of Science Meeting, Nov 1981.
1975 - 1978 Chairman Membership Committee, Bioenergetics Subgroup, Biophysical Society.

 

 

AWARDS, GRANTS, AND HONORS

2002 - 2005 Dept. Homeland Security, Oklahoma Memorial Institute for the Prevention of Terrorism.
2001 - 2006 NASA EPSCoR
2001 - 2007 US Army/NSF
2000 - 2001 NASA EPSCoR Research Initiation Grant
2000 - 2003 General Atomics
1999 - 2002 Oklahoma Health Research Program, State Of Oklahoma
1998 - 1999 U.S. Army
1994 - 1998 Oklahoma State University, Water Research Center
1991 - 1997 Office of Naval Research, U.S. Navy.
1991 - 1994 Applied Research Program, OCAST, State of Oklahoma.
1991 - 1994 Oklahoma Health Research Program, State of Oklahoma.
1989 - 1990 U. S. Air Force
1988 - 1990 Oklahoma Health Research Program, State of Oklahoma.
1985 - 1986 National Institute of Aging
1984 - 1988 U.S. Air Force
1983 - 1991 Oklahoma State University, Water Research Institute
1983 - 1984 American Heart Association, Oklahoma Affiliate
1980 - 1982 American Heart Association.
1977 - 1981 Oklahoma State University, Presidential Challenge Grants
1975 - 1977 Postdoctoral Fellowship from Institute of General Medical Science, National Institutes of Health.
1972 - 1974 National Institutes of Health

 

 

RESEARCH INTERESTS

  • Chemical and Biological Warfare Agent Sensors
  • Chemical Sensors
  • High Resolution Optical Spectroscopy
  • Photocatalytic Destruction of Organic Molecules including High Energy Compounds and Explosives

 

 

FUNDED GRANTS AS PRINCIPAL INVESTIGATOR

"Porphyrin-Mediated Photocatalytic Degradation of Energetic Materials; Phase 5" H.J. Harmon, Principal Investigator. National Science Foundation Jan 1 2007 to Dec 31, 2007. $960,000.

 

"Porphyrin-Mediated Photocatalytic Degradation of Energetic Materials; Phase 4" H.J. Harmon, Principal Investigator. US Army Defense Ammunition Center. Jan 1 2005 to Dec 31, 2006 $1,150,000.

 

"Porphyrin-Mediated Photocatalytic Degradation of Energetic Materials; Phase 3" H.J. Harmon, Principal Investigator. US Army Defense Ammunition Center. July 2003 to June 2004. $1,700,000.

 

"Field-Portable Chip-Based Anti-Terrorism Microanalyzer" H.J. Harmon, Co- Principal Investigator. Dept. of Homeland Security, Oklahoma City National Memorial Institute for the Prevention of Terrorism. December 2002 to Dec 2005. $565,220 of $2.4 M total.

 

"Porphyrin-Mediated Photocatalytic Degradation of Energetic Materials; Phase 2" H.J. Harmon, Principal Investigator. US Army Defense Ammunition Center. July 2002 to June 2003. $1,178,000.

 

"Porphyrin-Mediated Photocatalytic Degradation of Energetic Materials" H.J. Harmon, Principal Investigator. US Army Defense Ammunition Center. July 2001 to June 2002. $118,000.

 

"Second Generation Photocatalytic Oxidation Processes for the NASA Advanced Water Recovery System" H.J. Harmon, Principal Investigator. NASA EPSCoR, October 2001 to September 2006. $1,041,112.

 

"Bio-detection of Chemical Warfare Agents" H.J. Harmon, Principal Investigator. Oklahoma Health Research Program, June 1, 1999 to May 31, 2002. $135,000.

 

"Porphyrins as Chemical and Biological Defense Detector", H. James Harmon, Principal Investigator. US Army Edgewood Research Development and Engineering Center, Aberdeen Proving Grounds, MD. Aug 1, 1998 to Dec 31, 1998. $50,000.

 

"Development of Chemical Sensors Via Doped Sol-Gel Derived Media". H.J. Harmon and E.T. Knobbe. DOD/EPSCoR; Office of Naval Research, September 1, 1992 to August 31, 1997. $56,117 for graduate student stipends.

 

"pH Dependent Cytochrome Oxidase Oxygen Intermediates". H.J. Harmon, Principal Investigator, Oklahoma Health Research Program, September 1, 1991 to August 31, 1994. $89,544.

 

"Hazardous Material Detection by Doped Fiber Optics". H.J. Harmon and E.T. Knobbe, co principle investigators. Applied Research Program, Oklahoma Center for the Advancement of Science and Technology. January 1, 1992 to December 31, 1994. $190,327.

 

"Optical Probe Devices for Detecting Metal Analytes in Solution". H.J. Harmon and E.T. Knobbe, co principal investigators. Office of Naval Research, U.S.Navy. October 1, 1991 to August 31, 1997. $357,933.

"Acquisition of a Spectrophotometric Facility". H.J. Harmon and S.W. McKeever, co principal investigator, National Science Foundation, August 1, 1990 to July 31, 1991. $74,000.

 

"Effect of Hydrophobic Molecules on Mitochondria And Mitochondrial Proteins." H.J. Harmon, principal investigator, Air Force Office of Scientific Research, U. S. Air Force, August 1, 1989 to July 31, 1990. $60,016.

"Age Dependent Changes in Mitochondrial DNA From Brain." H.J. Harmon, principal investigator. Oklahoma Health Research Program, July 1, 1988 to June 30, 1990. $60,000.

 

"Effect of Aging on Heart and Brain Mitochondrial DNA" H.J. Harmon, principal investigator. National Institute of Aging Pilot Grant, 1985 1986.

"Interaction of Hydrophobic Molecules with Heme Proteins" H.J. Harmon, principal investigator. Air Force Office of Scientific Research, U.S. Air Force, August 1, 1984 to July 31, 1987. $167,933.

 

"Effect of Antiarrhythmic Drugs on Protein Structure" H.J. Harmon, principal investigator. Oklahoma Affiliate, American Heart Association, July 1, 1983 to June 30, 1984. $18,000.

 

"Isolation of Coupled Submitochondrial Particles" H.J. Harmon, principal investigator. American Heart Association, July 1, 1980 to June 20, 1982. $38,390.

 

"Metabolic Disorders of Hepatoma Mitochondria" H.J. Harmon, principal investigator. NIH, National Cancer Institute, Post doctoral Fellowship.

"Topography of Mitochondrial Respiratory Components" H.J. Harmon, principal investigator. NIH, General Medical Sciences, June 1, 1975 to May 31, 1977. NIH Post doctoral fellowship 1 F32 GM01997.

 

 

Grants Funded by the
Oklahoma State University Center for Water Research

"Photo-remediation of PAH-Contaminated Water" H. J. Harmon, principal investigator. July 1, 1994-present. $13,000.

 

"Development and Assembly of Fiber Optics Remote Sensing Unit for Determining Water Quality" H.J. Harmon, principal investigator. July 1, 1984 to June 30, 1985. $24,000.

 

"Development and Assembly of Fiber Optics Remote Sensing Unit for Determining Water Quality" H.J. Harmon, principal investigator. July 1, 1984 to July 30, 1984. $2437.

 

"Development and Assembly of Fiber Optics Remote Sensing Unit for Determining Water Quality" H.J. Harmon, principal investigator. July 1, 1983 to June 30, 1984. $18,000.

 

 

Grants Funded by the
Oklahoma State University Center Sensors and Sensor Technology

"Rapid Sequencing of DNA" H. James Harmon, Principal Investigator. July 1, 1999 to June 30, 1999. $3,000.

 

"Molecular Modelling of Porphyrins and Chemical Analytes" H. James Harmon, Principal Investigator. Feb 2, 1998 to June 30, 1999. $12,000.

 

Publications

Hikal, W.M. and H.J. Harmon. Early Events in TNT (2,4,6-Trinitrotoluene) Degradation by Porphyrins: Binding of TNT to Porphyrin by Hydrophobic and Hydrogen Bonds. Journal of Hazardous Materials, In press. (2008).

 

Harmon. H.J.. Role of Non-Linear Optics and Multiple Photon Absorbance in Enhancing Sensitivity of Enzyme-Based Chemical Agent Detectors. Methods. In press. (2008).

 

Cao, H., J. Nam, H.J. Harmon, and D. Branson. Spectroscopic Detection of Organophosphate Diazinon by Porphyrin Solution and Porphyrin-Dyed Cotton Fabric. Dyes and Pigments 74 (2007): 176-180.

 

Rahman, M. and H.J. Harmon. Inhibition of Aggregation of meso-tetra(4-sulfonatophenyl)porphyrin (H4TPPS) by Urea. Journal of Porphyrins and Phthalocyanines 11 (2007): 125-129.

 

Harmon, H.J. Reagentless Detection of CB Agents. Royal Society of Chemistry, Water Contamination Emergencies: Enhancing our Response. (2006): 284-291.

Harmon, H.J. Photocatalytic Demethylation of 2,4,6-trinitrotoluene (TNT) by Porphyrins. Chemosphere 63 (2006): 1094-1097.

 

Rahman, M. and H.J. Harmon. Absorbance Change and Static Quenching of Fluorescence of Meso-tetra(4-sulfonatophenyl)porphyrin (TPPS) by Trinitrotoluene (TNT). Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy 65 (2006): 901-906.

 

Johnson-White, B., A. Oliver, and H.J. Harmon. (M.K. Ram and V.R. Bhethanabotla, eds.) Reversible Inhibition of Enzymes for Optical Detection of Chemical Analytes. Chapter for Sensors for Chemical and Biological Applications, CRC Press, Taylor and Francis, Boca Raton, FL. (2006).

 

Immobilized Enzyme-Based Chemical Sensors. B.J. White and H.J. Harmon. (C.A. Grimes, E.C., Dickey, and M.V., Pishko, eds.) American Scientific Publishers. Encyclopedia of Sensors 5 (2006): 1-24.

 

Awawdeh, A.M. and H.J. Harmon. Spectroscopic Detection of Pentachlorophenol (PCP) in Water Using Immobilized and Water Soluble Porphyrins. Biosensors and Bioelectronics 20 (2005): 1595-1601.

 

Awawdeh, A.M. and H.J. Harmon Spectrophotometric Detection of Pentachlorophenol (PCP) in Water Using Water Soluble Porphyrins. Sensors and Actuators B 106 (2005): 234-242.

 

White, B.J. and H.J. Harmon. Competitive Inhibition of Carbonic Anhydrase by Water Soluble Porphyrins: Use of Carbonic Anhydrase as a CO2 Sensor. Sensor Letters 3 (2005): 59-65.

 

White, B.J. and H.J. Harmon. Optical Determination of Bacterial Exosporium Sugars Using Immobilized Porphyrins. IEEE Sensors Journal 5 (2005): 726-732.

White, B.J. and H.J. Harmon. Optical Solid-State Detection of Organophosphates Using Organophosphate Hydrolase. Biosensors and Bioelectronics 20 (2005): 1977-1983.

 

White, B.J. and H.J. Harmon. (C.A. Grimes, E.C., Dickey, and M.V., Pishko, eds.) Immobilized Enzyme-Based Chemical Sensors. Chapter in Encyclopedia of Sensors 5 (2005): 1-24.

 

White, B.J. and H.J. Harmon. Enzyme-based Detection of GB (Sarin) Using Planar Waveguide Absorbance Spectroscopy. Sensor Letters 3 (2005): 36-41.

 

White, B.J. and H.J. Harmon. Optical Enzyme-based Sensors for Reagentless Detection of Chemical Analytes. Chapter for American Chemical Society book Polymers and Materials for Anti-Terrorism and Homeland Defense. In press. (2005).

 

White, B.J., J.A. Legako, and H.J. Harmon. Interaction of Dipicolinic Acid with Water Soluble and Immobilized Porphyrins. Sensors and Actuators B. 97 (2004): 277-283.

 

Awawdeh, M.A., J.A. Legako, and H.J. Harmon. Solid-State Optical Detection of Amino Acids. Sensors and Actuators B. 91 (2003): 227-230.

 

White, B.J., A.J. Legako, and H.J. Harmon. Spectrophotometric Detection of Cholinesterase Inhibitors with an Integrated Acetyl-/Butyrylcholinesterase Surface. Sensors and Actuators B. 89 (2003): 107-111.

 

Legako, J.A., B.J. White, and H.J. Harmon. Optical Detection of Cyanide using Immobilized Porphyrins. Sensors and Actuators B. 91 (2003): 128-132.

 

White, B.J., J.A. Legako, and H.J. Harmon. Rapid Reagent-less Detection of Competitive Inhibitors of Butyrylcholinesterase. Sensors and Actuators B 91 (2003): 138-142.

 

Harmon, H.J. Specific Visible Spectrum Changes in Cytosine-Functionalized Porphyrin Induced by Guanine Binding. Porphyrins and Phthalocyanines 6 (2002): 73-77.

 

White, B.J. and H.J. Harmon. Interaction of Monosulfonate Tetraphenyl Porphyrin, a Competitive Inhibitor, with Acetylcholinesterase. Biosensors and Bioelectronics 17 (2002): 63-469.

 

White, B.J., J.A. Legako, and H.J. Harmon. Reagentless Detection of a Competitive Inhibitor of Immobilized Acetylcholinesterase. Biosensors and Bioelectronics 17 (2002): 361-366.

 

White, B.J. and H.J. Harmon. Novel Optical Solid-State Glucose Sensor Using Immobilized Glucose Oxidase. Biochemical and Biophysical Research Communications 296 (2002): 1069-1074.

 

Harmon, H.J. Porphyrins as CB Detectors. Proceedings of the First Joint Conference on Point Detection for Chemical and Biological Defense. (2001).

 

Harmon, H.J. Spectroscopic Determination of Acetylcholine Esterase-Inhibitor Complex: Determination of Conformational Shifts of Proteins. Biosensors and Bioelectronics 16 (2001): 1035-1041.

 

Ma, K.K. and H.J. Harmon. Properties Influencing a Water Splitting Photocatalytic Electron Generator Reaction. Proceedings of the Research Experience for Undergraduates meeting, Louisville, KY. (2001).

 

McCoy, J.K., H.J. Harmon, T.A. Baird, and S.F. Fox. Geographic Variation in Sexual Dichromatism in the Collared Lizard, Crotaphytus collaris, (Sauria: Crotaphytidae). Copeia (1997): 565-571.

 

Yates, L.M., D. Arbuthnot, H.J. Harmon, and E.T. Knobbe.Sol-Gel Derived Sensor Materials for Use in Aqueous Transition Metal Ion Detection. Materials Research Society Symposium 286 (1993): 265-270.

 

Beach, A.C. and H.J. Harmon. Additive Effects and Potential Inhibitory Mechanism of Some Common Aromatic Pollutants on in vitro Mitochondrial Respiration. Biochemical Toxicology 7 (1992): 19-25.

 

Usui, S., L. Yu, H.J. Harmon, and C. A. Yu. J. Arch. Immunological Study of Subunit VI (Mr 13,400) of Mitochondrial Ubiquinol-Cytochrome c Reductase. Biochem. Biophys. 289 (1991): 109-117.

 

Harmon, H.J. Effect of Age on Kinetics and Carbon Monoxide Binding to Cytochrome Oxidase in Synaptic and Non-synaptic Brain Mitochondria. Mechanisms of Ageing and Development 53 (1990): 35-48.

 

Harmon, H.J. and B. K. Stringer. Effect of pH on CO Recombination to Cytochrome Oxidase in Intact Mitochondria. FEBS Letters 267 (1990): 167-170.

 

Harmon, H.J. Lack of Age-Dependent Changes in CO Binding to Cardiac Mitochondrial Cytochrome Oxidase. Mechanisms of Ageing and Development 55 (1990): 151-159.

 

Stringer, B.K. and H.J. Harmon. Inhibition of Cytochrome Oxidase by Dibucaine. Biochemical Pharmacology 40 (1990): 1077-1081.

 

Harmon, H.J. Conversion of Dual Wave Beam Spectrophotometer to Dual Wavelength Spectrophotometer. U. S. Patent #4 (1990): 929, 078.

 

Harmon, H.J. Effect of Naphthalene on Cytochrome Oxidase Activity. Bull. Environ. Contam. Toxicol. 40 (1988): 105-109.

 

Harmon, H.J. Electron Redistribution in Mixed Valence Cytochrome Oxidase Following Photolysis of Carboxy-Oxidase. Bioenergetics and Biomembranes 20 (1988): 735-748.

 

Harmon, H.J. Determination of the Orientation of Membrane Vesicles Derived from Mitochondria. Journal of Bioenergetics and Biomembranes 19 (1987): 167-189.

 

Harmon, H.J., S. Nank, and R.A. Floyd. Age-dependent Change in Rat Brain Mitochondria of Synaptic and Non-Synaptic Origins. Mechanisms of Ageing and Development 38 (1987): 167-177.

 

Manzelmann, M.S. and H.J. Harmon. Lack of Age-Dependent Changes in Rat Heart Mitochondria. Mech. Ageing. Dev. 39 (1987): 281-288.

 

Struble, V.G. and H.J. Harmon. Effect of Naphthalene on Soil and Fresh-Water Algae. Proceedings of Second International Conference on Groundwater Quality Research, Oklahoma State University, Stillwater (1985): 214-216.

 

Ohnishi, T. H.J. Harmon, and A.J. Waring. EPR studies on the Spatial Relationship of Redox Components in Cytochrome Oxidase. Biochem. Soc. Transactions 13 (1985): 607-612.

 

Floyd, R.A., M.M. Zaleska, and H.J. Harmon. (D. Armstrong, R.S. Sohal, R.G. Cutler, and T.F. Slater, eds.) The Possible Involvement of Iron and Oxygen Free Radicals in Aspects of Aging in BrainIn Free Radicals in Molecular Biology, Aging, and Disease. Raven Press, N.Y. (1984): 143-162.

 

Harmon, H.J. Molecular Basis for Inhibition of Mitochondrial Respiration by Naphthalene. V.G. Struble and Bulletin of Environmental Contamination and Toxicology 31 (1983): 644-648.

 

Darville, R.G., H.J. Harmon, M.R. Sanborn, and J. Wilhm. Effect of Naphthalene on the Hemolymph Ion Concentrations of Chironomus attenuatus and the Possible Mode of Action. Environmental Toxicology and Chemistry 2 (1983): 423-429.

 

Harmon, H.J. and V.G. Struble.Effects of 2-Hydroxy-3-Undecyl-1, 4-Naphthoquinone on Respiration of Electron Transport Particles and Mitochondria: Topographical Location of the Rieske Iron-Sulfur Protein and the Quinone Binding Site. Biochemistry 22 (1983): 4394-4400.

 

Harmon, H.J. and P.F. Basile. Differential Exposure of Components of Cytochrome b-c1 Region of Beef Heart Mitochondria and Electron Transport Particles. Journal of Bioenergetics and Biomembranes 14 (1982): 23-43.

 

Crider, J.Y., J. Wilhm, and H.J. Harmon. The Effects of Naphthalene on the Hemoglobin Concentration and Oxygen Uptake of Daphnia magna. Bulletin of Environmental Contamination and Toxicology 28 (1982): 52-57.

 

Harmon, H.J. and M.R. Sanborn. Effects of Naphthalene on Respiration in Heart Mitochondria and Intact Cultured Cells. Environmental Research 29 (1982): 160-173.

 

Harmon, H.J. Isolation of Totally Inverted Submitochondrial Particles by Sonication of Beef Heart Mitochondria. Journal of Bioenergetics and Biomembranes 14 (1982): 377-386.

 

Ohnishi, T., H.Blum, H.J. Harmon, and T. Hompo. Location of Rieske Iron-Sulfur Cluster in the Mitochondrial Membrane. In Electron Transport and Oxygen Utilization Elsevier/North-Holland (1980): 387-393.

 

Harmon, H.J. and M. Sharrock. The Effect of Mitochondrial Energization on Cytochrome c Oxidase Kinetics as Measured at Low Temperatures I. The Reaction with Carbon Monoxide. Biochim. Biophys. Acta 503 (1978): 56-66.

 

Harmon, H.J. and M.K.F. Wikstrom. The Effect of Mitochondrial Energization on Cytochrome c Oxidase Kinetics as Measured at Low Temperatures II. The Binding and Reduction of Dioxygen. Biochim. Biophys. Acta 503 (1978): 67-77.

 

Blum, H., H.J. Harmon, J.S.Leigh, J.C. Salerno, and Britton Chance. The Orientation of a Heme of Cytochrome c Oxidase in submitochondrial Particles. Biochim. Biophys. Acta 502 (1978): 1-10.

 

Salerno, J.C., H.J. Harmon, H.Blum, J.S. Leigh, and T. Ohnishi. A Transmembrane Quinone Pair in the Succinate Dehydrogenase-Cytochrome b Region. FEBS Letters 82 (1977): 175-182.

 

Wikstrom, M.K.F., H.J. Harmon, W.J.Ingledew, and B. Chance. A Re-evaluation of the Spectral, Potentiometric, and Energy-Linked Properties of Cytochrome c Oxidase in Mitochondria. FEBS Letters 65 (1976): 259-277.

 

Harmon, H.J. and F.L. Crane. Inhibition of Mitochondrial Electron Transport by Hydrophilic Metal Chelators; Determination of Dehydrogenase Topography. Biochim. Biophys. Acta 440 (1976): 45-58.

 

Chance, B., C. Saronio, H.J. Harmon, and M.K.F. Wikstrom. Mechanism of Electron Transfer in Site III. Abs. to International Symposium on Electron-Transfer Chains and Oxidative Phosphorylation, September 15-18, Fasano, Italy. (1975).

 

Chance, B., H.J. Harmon, and M. Wikstrom Molecular Events in Energy Coupling Reactions: The Effect of Energization Upon the Formation and Interconversion of Oxygen Compounds of Cytochrome Oxidase, in Electron Transfer Chains and Oxidative Phosphorylation. North-Holland, Amsterdam (1975): 81-95.

 

Chance, B., H.J. Harmon, and C. Saronio. Cytochrome Oxidase Oxygen Intermediates. Proc. 10th FEBS Meeting, North-Holland, Amsterdam 40 (1975): 187-194

 

Harmon, H.J. and F.L. Crane. Topography of Inner Mitochondrial Membrane. Indiana Academy of Sciences. 83 (1974): 105-112.

 

Harmon, H.J. and F.L. Crane. Topographical Definition of New Sites on the Mitochondrial Electron Transport Chain. Biochem. Biophys. Res. Comm. 59 (1974): 326-333.

 

Harmon, H.J., J.D. Hall, and F.L. Crane. Structure of Mitochondrial Cristae Membranes. Biochim. Biophys. Acta 344 (1974): 119-156.

 

Phelps, D.C., H.J. Harmon, and F.L. Crane. Prevention by Uncouplers of Lipophilic Chelator Inhibition at Three Sites of Mitochondrial Electron Transport. Biochem. Biophys. Res. Comm. 59 (1974): 1185-1191.

 

Harmon, H.J. and F.L. Crane. Inhibition of Cytochrome c Oxidase by Hydrophobic Metal Chelators. Biochim. Biophys. Acta 368 (1974 ): 125-129.

 

Crane, F.L. Topography and Function of Metallo-Proteins in Cristae Membranes. Ph.D. Thesis, Advisor. (1974)

INVITED PAPERS

Role of Non-Linear Optics and Multiple Photon Absorbance in Enhancing Sensitivity of Enzyme-Based Chemical Agent Detectors. H. James Harmon. Methods. In press.

 

Reversible Inhibition of Enzymes for Optical Detection of Chemical Analytes. B.J. White, A. Oliver, and H.J. Harmon. Chapter for CRC Press Chemical and Biological Applications. In press.

 

Immobilized Enzyme-Based Chemical Sensors. B.J. White and H.J. Harmon. Chapter in Encyclopedia of Sensors, 5, 1-24 (Grimes, C.A., Dickey, E.C., and Pishko, M.V. eds).

 

Optical Enzyme-based Sensors for Reagentless Detection of Chemical Analytes, B.J. White and H.J. Harmon. Chapter for American Chemical Society book Polymers and Materials for Anti-Terrorism and Homeland Defense. In press.

PATENTS

Broad Spectrum Bio-Detection of Nerve Agents, Organophosphates, and Other Chemical Warfare Agents. H.J. Harmon. U.S. Patent #6,821,738.

 

Conversion of Dual Wave Beam Spectrophotometer to Dual Wavelength Spectrophotometer. H.J. Harmon. U. S. Patent # 4,929,078.

 

 

PRESENTATIONS AT MEETINGS/SYMPOSIA

2007 "Photocatalytic Mineralization of TNT and Destruction of RDX Using Immobilized Porphyrins", J. Robinson, Clint Conner, M. Rahman, Solim Kwak, and H.J. Harmon. JANNAF 34th Propellant and Explosives Development and Characterization Subcommittee and 22nd Safety and Environmental Protection Subcommittee Joint Meeting, August 13-18, 2007. Reno, NV.
2007 "Reagentless Real-Time Optical Biodetection using Biomimetic Receptors" H. J. Harmon, Scentzar First Annual Biological Sampling and Detection Symposium, Richmond, VA, April 30- May 2, 2007.
2007 "Photocatalytic Destruction of TNT" H. J. Harmon, Global Demilitarization Symposium and Exposition, Reno, NV May 2007.
2007 "Optical Biodetection Using Nanolayer Biomimetic Receptors in Real Time", H. J. Harmon, Nanoelectric Devices for Defense & Security (NANO-DDS) Conference, Crystal City Washington, DC June 18-21, 2007.
2007 "Reagentless Hand-Held Real-Time Evanescent Optical Chem-Bio Detection Using Biomimetic Receptor and Ligand Nanosurfaces", H. J. Harmon and Amanda Oliver. NDIA/Defense Alliance of Minnesota "Heatrland Security" Conference and Exposition, July 9-11, 2007, Minneapolis, MN.
2007 "Photoreduction of Perchlorate to Chloride by Immobilized Porphyrins", H.J. Harmon, Jason Robinson, and Solim Kwak. JANNAF 34th Propellant and Explosives Development and Characterization Subcommittee and 22nd Safety and Environmental Protection Subcommitee Joint Meeting, August 13-18, 2007. Reno, NV.
2007 "Reagentless Real-time Evanescent Optical Chem- and Biodetection Using Biomimetic Receptors and Ligands" H.J. Harmon and Amanda Oliver, 5th Annual Federal CBRN Detection Symposium, Washington, DC May 31-June 1, 2007.
2006 "Detection of Influenza Virus Using Porphyrin-Based Biomimetic Natural Ligands and Receptors" Amanda Oliver and H.J. Harmon.Biosensors 2006: 9th World Congress on Biosensors, May 10-12, 2006, Toronto, Canada.
2006 "Detection of Cholera Toxin Using Natural Biomimetic Receptors and Ligands" Amanda Oliver and H.J. Harmon. Biosensors 2006: 9th World Congress on Biosensors, May 10-12, 2006, Toronto, Canada.
2006 "Optical Detection of Chem-Bio Agents Using Monalayer Proteins and Enzymes on a Planar Waveguide" PITTCON March 12-17 2006. Orlando, FL.
2006 "Photocatalytic Destruction of TNT" Global Demilitarization Symposium and Exposition, Indianapolis, IN. May 2-5, 2006.
2006 "Reagentless Real-Time Optical Buidetection using Biomimetic Receptors" International Symposium on Spectral Sensing Research (ISSSR), Bar Harbor, ME, May 29-June 2, 2006.
2006 "Reagentless Real-Time Optical Biodetection Using Biomimetic Receptors" Amanda Oliver and H.J. Harmon. 2006 Scientific Conference on Chemical and Biological Defense Research. Hunt Valley, MD. Nov 13-15, 2006.
2006 "A New Generation of Biosensors: Real-Time Reagentless Solid-State Optical Detection Using "Biomimetic" Naturally-Occurring Receptors and Ligands" H.J. Harmon and Amanda Oliver. Biosensors 2006: 9th World Congress on Biosensors, May 10-12, 2006, Toronto, Canada.
2006 "Detection of T-antigen Using a Solid-State Monolayer of Immobilized Biomimetic Receptor Molecules" H.J. Harmon and Amanda Oliver. Biosensors 2006: 9th World Congress on Biosensors, May 10-12, 2006, Toronto, Canada.
2005 "Reagentless Detection of CB Agents" to Water Contamination Emergencies: Enhancing our Response" June 2005, Manchester, UK.
2005 "Real-Time Reagentless Agent and Analyte Detection and Identification". H.J. Harmon. Biodetection Technologies Technological Responses to Biological Threats" Meeting, June 9-10, 2005. Baltimore, MD. Invited Talk
2005 "Optical Real-Time Detection Using Nanolayer Determinants" H. James Harmon and A. Oliver. Photonic Nanosystems 2005/MEMS & BioMEMS 2005: Biodetection Technologies - Sensing, Detection, Identification with Nanophotonics and MEMS. November 8, 2005, San Francisco, CA.
2005 "Optical Detection Using Protein and Enzyme Monolayers on Planar Waveguides" August 18, 2005, Rochester, NY.
2005 "480-day Lifetime of Reagentless Real-Time Optical Detector of Nerve Agents and Related Compounds". H.J. Harmon, 2005 Scientific Conference on Chemical and Biological Defense Research, Timonium, MD. Nov. 14-16, 2005
2005 "Photocatalytic Destruction of TNT" Global Demilitarization Symposium and Exposition, Reno, NV. May 9-12, 2005.
2004 "Competitive Inhibition of Carbonic Anhydrase by a Water Soluble Porphyrin", B.J. White and H.J. Harmon. Biosensors 2004, Granada Spain, May 24-26, 2004.
2004 Picogram GB Detection Using Immobilized Cholinesterase on a Solid-State Reagentless Platform. H.J. Harmon and B.J. White. 2004 Joint Service Scientific Conference on Chemical & Biological Defense Research. Nov 15-17, 2004. Hunt Valley, MD.
2004 "Spectroscopic Determination of Pentachlorophenol (PCP) in Drinking Water Using Porphyrin" M. Awawdeh and H.J. Harmon. Biosensors 2004, Granada Spain, May 24-26, 2004.
2004 "Optical Solid-State Detection of Organophosphates Using Organophosporus Hydrolase". B.J. White and H.J. Harmon. Biosensors 2004, Granada Spain, May 24-26, 2004.
2004 "Real-Time Reagentless Detection of CBW Agents". B.J. White and H.J. Harmon. Biodetection Technologies Workshop of Mobile Detection Lab at Biodetection Technologies Technological Responses to Biological Threats" Meeting, June 17-18, 2004, Washington DC. Invited Talk.
2004 "Porphyrin-Mediated Photocatalytic Destruction of TNT at the OSU-DAC Energetic Materials and Sensor Research Facility" H.J. Harmon and S. Kwak. JANNAF 32st Propellant Development and Characterization and 21st Safety and Environmental Protection Subcommittee Joint Meeting. Seattle. July 25-29, 2004.
2004 "Porphyrin-Mediated Photocatalytic Destruction of TNT at the DAC-OSU Energetic Materials and Sensor Research Center", H.J. Harmon and Solim Kwak, 12th Global Demil Symposium and Exhibition, Dallas, TX, May 17-21, 2004.
2004 "Porphyrin-Mediated Photocatalytic Destruction of TNT at the OSU-DAC Energetic Materials and Sensor Research Facility" H.J. Harmon and S. Kwak. JANNAF 32st Propellant Development and Characterization and 21st Safety and Environmental Protection Subcommittee Joint Meeting. Seattle. July 25-29, 2004.
2003 "Metalloporphyrin Photocatalytic Modification of Nitro-Energetic Compounds". H.J. Harmon and Solim Kwak. JANNAF 31st Propellant Development and Characterization and 20th Safety and Environmental Protection Subcommittee Joint Meeting. Charlottesville, VA Mar 25-27, 2003.
2003 "Second Generation Photocatalytic Oxidation Processes for the NASA Advanced Water Recovery System". Bioastronautics Investigators’ Workshop. Galveston, TX. Jan. 13-15, 2003.
2003 "Energetic Materials and Sensor Center" H. J. Harmon and Solim Kwak, 12th Demil Users Group Meeting, Atlanta, GA, Oct. 29, 2003.
2003 "Metalloporphyrin Photocatalytic Modification of Nitro-Energetic Molecules". H.J. Harmon, T.C. Collins, and Solim Kwak. 11th Global Demil Symposium and Exhibition, Sparks, NV, May 19-22, 2003.
2002 "Real-time Reagentless Detection of Chemicals and Chemical Agents at Sub-ppb Levels". Workshop on Sensors for the Aircraft Cabin Environment, sponsored by FAA Center of Excellence for Airliner Cabin Environment Research. Jan. 19-20, 2005, Everett, WA.
2002 "Rapid Reagent-less Optical Detection of Inhibitors of Butyrylcholinesterase". B.J. White, J.A. Legako, and H.J. Harmon. 2002 Joint Service Scientific Conference on Chemical and Biological Defense Research. Hunt Valley, MD. Nov. 19-21, 2002.
2002 "Metalloporphyrin Photocatalytic Modification of Nitro-Energetic Molecules. H.J. Harmon and Solim Kwak. 11th Demil Users Group Meeting, San Diego, CA. October 29-30, 2002.
2002 "Optical Detection of Cyanide using Immobilized Porphyrins. J.A. Legako, B.J. White, and H.J. Harmon. 9th International Meeting on Chemical Sensors, Boston, MA. July 7-10, 2002.
2002 "Rapid Reagent-less Optical Detection of Inhibitors of Butyrylcholinesterase". B.J. White, J.A. Legako, and H.J. Harmon. 9th International Meeting on Chemical Sensors, Boston, MA. July 7-10, 2002.
2002 "Solid-State Optical Detection of Amino Acids". M.A. Awawdeh, J.A. Legako, and H.J. Harmon. 9th International Meeting on Chemical Sensors, Boston, MA. July 7-10, 2002.
2002 "Metalloporphyrin Photocatalytic Modification of Nitro-Energetic Molecules". H.J. Harmon and Solim Kwak. 10th Global Demil Symposium and Exhibition, Lexington, KY, May 20-24, 2002.
2001 "Porphyrins as CB Detectors". H.J. Harmon. Proceedings of the First Joint Conference on Point Detection for Chemical and Biological Defense.
2000 Two Porphyrin Binding Sites on Bovine Serum Albumin. H. James Harmon. American Society for Biochemistry and Molecular Biology, Boston, MA, June 4-8, 2000.
2000 "Extended Lifetime of Reagentless Detector for Multiple Inhibitors of Acetylcholinesterase". B.J. White, J.A. Legako, and H.J. Harmon. Biosensors 2002, Kyoto, Japan. May 15-17, 2002.
2000 "Properties Influencing a Water Splitting Photocatalytic Electron Generator Reaction". K.K. Ma and H.J. Harmon. Research Experience for Undergraduates meeting, Louisville, KY.
1999 Real-Time Solid-State Chem/Biol Sensor for First Responders, Military and Civil Personnel. H. James Harmon. "Research in Domestic Preparedness: Ensuring Security, Protecting Infrastructure, and Preventing Violence" Sponsored by AAAS. Oklahoma State University, March 14-16, 1999.
1998 pH-Dependent Spectra of Carboxy- and Cyano-Cytochrome Oxidase. H. J. Harmon, Biophysical Society, Kansas City KS, February 22-26, 1998.
1997 Spectral Memory in Cytochrome Oxidase Ascertained by pH-Jump Spectroscopy. H. J. Harmon, Biophysical Society, New Orleans, LA, March 2-6, 1997.
1995 pH-Dependent Carboxy Cytochrome Oxidase Spectra. H.J. Harmon, Biophysical Society, San Francisco, February 12-16, 1995.
1994 Salt-Induced Dimerization of Tetraphenylporphyrin Sulfonate. H.J. Harmon, ASBMB, Washington, D.C., May 19-22, 1994.
1994 Uncoupler Inhibition of Oxygen Intermediate Formation in Cytochrome Oxidase. H.J. Harmon, Biophysical Society, New Orleans, March 6-10, 1994.
1993 Na+-Induced Dimer Formation of Tetraphenylporphyrin (TPPS). H.J. Harmon and E.T. Knobbe. ASBMB, San Diego, May 31-June 3, 1993.
1993 New Intermediate State Involved in CO Rebinding to Cytochrome Oxidase. H.J. Harmon, Biophysical Society, Washington, D.C., Feb. 15-18, 1993.
1992 Sol-Gel Derived Sensor Materials for Use in Aqueous Transition Metal Ion Detection. L.M. Yates, D. Arbuthnot, H.J. Harmon, and E.T. Knobbe. Materials Research Society, Boston.
1992 The pH-Sensitive Site of CO Recombination to Cytochrome Oxidase is Located on the C-Side. H.J. Harmon, joint meeting ASBMB/Biophysical Society, Houston, Feb. 9-13, 1992.
1991 pH-Dependent and Energy-Linked CO Binding to Cytochrome Oxidase in Intact Mitochondria. H.J. Harmon and B. K. Stringer, Biophysical Society, San Francisco, Feb. 24-28, 1991.
1990 pH-Dependent CO Recombination in Cytochrome Oxidase. H.J. Harmon and B. K. Stringer, ASBMB meeting, New Orleans, June, 1990.
1990 Effect of pH on CO Recombination in Cytochrome Oxidase. B. K. Stringer and H.J. Harmon, Biophysical Society, Feb. 18-22, 1990, Baltimore, MD, Biophys. J. 57, 563a.
1990 Aging Effects on CO Binding to Cytochrome Oxidase. H.J. Harmon. Biophysical Society, Feb. 18-22, 1990, Baltimore, MD, Biophys J. 57, 562a.
1989 Additive Effects of Three Polynuclear Aromatic Hydrocarbons on Mitochondrial Respiration. A. C. Beach and H.J. Harmon Biophysical Society, Feb 12-16, Cincinnati, OH. Biophys. J. 55, 571a.
1989 Site of Inhibition of Cytochrome c Oxidase by Dibucaine. B. K. Stringer and H.J. Harmon. Biophysical Society, Feb. 12-16, Cincinnati, OH. Biophys J. 55, 30a.
1988 Effect of Propranolol and Local Anesthetics on Myoglobin and Cytochrome Oxidase. H.J. Harmon and B. Lukas. FASEB Annual Meeting. May 1-5, Las Vegas, NV.
1987 Detection of Environmental Contaminants by Fiber Optic Spectroscopy. H. James Harmon. Society of Environmental Toxicology and Chemistry. Nov. 9-12, Pensacola, FL.
1987 Effects of Local Anesthetics and Cardiac Antiarrhythmics on Mitochondrial Cytochrome Oxidase Activity. B. Stringer and H.J. Harmon. Okla. Acad. Science. Nov. 13, 1987, Alva, OK.
1987 Electron Redistribution in Cytochrome Oxidase at Low Temperatures. H.J. Harmon. American Society of Biological Chemists. June 7-11, 1987, Philadelphia.
1986 Effect of Cardiac Antiarrhythmics and Anesthetics on Cytochrome Oxidase Activity. H.J. Harmon and J. Swartz. American Society of Biological Chemists. June 9-12, 1986, Washington, D.C.
1985 Non-fusion Penetration of the Host Cell Membrane by Sendai Virus. M.R. Sanborn, G.C. Keyser, H.J. Harmon, and S.J. Stahl. ADM Conference on Virus Attachment, Philadelphia, PA, April, 1985.
1985 Interaction of Local Anesthetics with Mitochondrial Cytochromes and Myoglobin. H. James Harmon. American Society of Biological Chemists, FASEB meeting, Anaheim, April 21-26, 1985.
1984 02 Radical Production by Rat Brain Mitochondria as Influenced by Age. R.A. Floyd, H. James Harmon, and S.K. Nank. Biophysical Society, San Antonio Feb., 1984.
1984 Topographical Location of Mitochondrial Respiratory Components. H. James Harmon. Invited symposium speaker. Southwest Regional American Chemical Society Meeting. December 5, 1984, Lubbock, Texas.
1984 EPR studies on the Spatial Relationship of Redox Components in the Cytochrome Oxidase. T. Ohnishi, H.J. Harmon, and A.J. Waring. Biochemical Society, Leeds, England, July, 1984.
1984 The Possible Involvement of Iron and Oxygen Free Radicals in Aspects of Aging in Brain. R.A. Floyd, M.M. Zaleska, and H.J. Harmon. "ESR Conference of the Royal Society of Chemistry", March 1984, Oxford.
1984 Effect of Polycyclic Aromatic Hydrocarbons on Soil and Fresh-Water Algae. H.J. Harmon and V.G. Struble. Second International Conference on Ground Water Quality Research, Tulsa, OK, March, 1984.
1984 Changes in Iron Content and Oxidative Damage in Aging Rat Brain. M.M. Zaleska, H.J. Harmon, and R.A. Floyd. American Society of Biological Chemists, St. Louis, June, 1984.
1984 Age-Dependent Changes in Mitochondrial Respiration and O2 Generation in Rat Brain Mitochondria. H.J. Harmon, S. Nank, and R. A. Floyd. American Society of Biological Chemists Meeting, St. Louis, June, 1984.
1984 Interaction of Local Anesthetics with Cytochrome c. H. James Harmon. Biophysical Society, San Antonio, Feb., 1984.
1983 Evidence for Non-Fusion Entry of Sendai Virus into Host Cells. M.R. Sanborn and H.J. Harmon. Amer. Society for Microbiology, New Orleans.
1983 Topographical Location of the Rieske Fe-S Center in Mitochondria. V.G. Struble and H.J. Harmon. Biophysical Society, San Diego.
1983 Effect of Lidocaine on the Physico-Chemical Characteristics of Cytochrome c. H.J. Harmon. Biophysical Society, San Diego.
1982 Use of Mitochondrial Respiration to Determine Toxicity. H.J. Harmon, M.R. Sanborn, J.A. Bantle, J. Wilhm, S.L. Burks. American College Toxicology First World Congress on Toxicology and Environmental Health. Washington, D.C. May 26-30, 1982.
1982 H+ Stoichiometry in Beef Heart Submitochondrial Particles. H. James Harmon. Biophysical Society, Boston, Biophys. J. 37.
1982 Ion Leakage from Lipid Vesicles Exposed to PAH. Roy Darville and H.J. Harmon. Oklahoma Academy of Science, Nov, 1981.
1981 The Inhibition of Na, K ATPase by Naphthalene. Roy Darville and H.J. Harmon. Oklahoma Academy of Science, Nov, 1981.
1981 Effect of Naphthalene and other Aromatic Hydrocarbons on Respiration of Isolated Heart Mitochondria, H.J. Harmon and M.R. Sanborn. Oklahoma Academy of Science, Nov, 1981.
1981 Effect of Naphthalene and other Aromatics on Respiration and Morphology of Intact Culture Cells. M.R. Sanborn, and H.J. Harmon. Oklahoma Academy of Science, Nov, 1981.
1981 Energy-linked Proton Translocation in Submitochondrial Particles. H. James Harmon. Oklahoma Academy of Science Nov, 1981.
1981 Effect of Naphthalene on Respiration in Heart Mitochondria and Intact Cultured Cells. H.J. Harmon, R.A. Browning, M.R. Sanborn and N.N. Durham. American Society for Microbiology Annual meeting, Dallas, March 1-6, 1981.
1981 Submitochondrial Particles are Not "Hybridized" or "Scrambled". H.J. Harmon and J.M. Kunkel. Biophysical Society Annual Meeting, Denver Feb 22-25, 1981. Biophys. J. 33, 99a.
1980 Location of the Rieske Iron-Sulfur Cluster in the Mitochondrial Membrane. T. Ohnishi, J.Blum, H.J. Harmon, and T. Hompo, Conference on Electron Transport, April, 1980.
1980 Location of Cytochromes b and c1 in Ubiquinol-Cytochrome c Reductase in Beef Heart Mitochondria. H. James Harmon. Biophysical Society/ASBC Annual Meeting, New Orleans June 1-5, 1980.
1979 Topographical Location of Cytochromes b on Each Face of the Inner Mitochondrial Membrane. H.J. Harmon and P.F. Basile. Biophysical J. 25, 277a. Biophysical Society, Atlanta Feb. 25, 1979.
1978 Effect of Membrane Energization on the Binding of CO to Mitochondrial Cytochrome c Oxidase. H.J. Harmon and M. Sharrock. Proc. VIth International Congress of Biophysics, Kyoto, Japan Sept. 1978.
1978 Sequence of Events in the Reduction of O2 by Cytochrome Oxidase. H.J. Harmon. Biophysical J. 21, 34a.
1977 Effect of pH on Formation of Cytochrome c Oxidase Oxygen Intermediates. H.J. Harmon. FASEB Meeting, Chicago.
1977 Heme Plane Orientation in Mitochondrial Membranes. J.S. Leigh, Jr. and H.J. Harmon. Biophysical J. 17, 24la.
1977 Effect of Membrane Energization on the Binding of CO and Oxygen by Mitochondrial Cytochrome c Oxidase at Low Temperatures. H.J. Harmon and M. Sharrock. Biophysical J. 17, 25la.
1976 Effect of Bathophenanthroline and Protamine Sulfate on Cytochrome Oxidase Intermediates. H.J. Harmon, M. Wikstrom and B. Chance, Xth International Congress of Biochemistry, Hamburg, 1976.
1976 Effect of Energization on Cytochrome c Oxidase Oxygen Intermediates. H.J. Harmon, B. Chance, and M.K.F. Wikstrom. Biophysical J. 16, 135a (1976).
1976 Re-evaluation of the Spectral, Redox, and Energy-lined Properties of Cytochrome a and a3. M.K.F. Wikstrom, H.J. Harmon, W.J. Ingledew, and B. Chance, Xth International Congress of Biochemistry, Hamburg, 1976.
1976 Electron Transport and Energy Coupling in Intermediates of Oxygen Reduction in Mitochondrial and Solubilized Cytochrome Oxidase. B. Chance, H.J. Harmon and M.K.F. Wikstrom, Xth International Congress of Biochemistry, Hamburg, 1976.
1975 Uncoupler-Prevented Metal Chelator Inhibitions of Mitochondrial Cytochrome c Oxidase. 1975 FASEB Meeting, Atlantic City. Fed. Proc. 34, 487, Abs. #1500.
1974 Chelator Inhibition of Metallo-Protein Function in Biological Electron Transport (with F.L. Crane, R. Barr and R.T. Crane) 1974 ACS Great Lakes Regional Meeting, West Lafayette, Indiana.
1974 Evidence for Transmembrane Orientation of Dehydrogenase Complexes in Mitochondrial Cristae. Fed. Proc. 33, 1292, Abs. #397, 1974. Biochemistry/Biophysics Meeting, Minneapolis.
1974 Energy Linked Chelator Inhibition at Three Sites of Mitochondrial Electron Transport (with D.C. Phelps and F.L. Crane) September 12, 1974, Atlantic City, ACS Meeting.
1973 Topography of Inner Mitochondrial Membrane (with F.L. Crane) Indiana Academy of Sciences, October 27, 1973, Indianapolis.
1973 Topography of Ferricyanide/Ferrocyanide Reaction Sites in Mitochondrial Membranes (with F.L. Crane) American Society of Cell Biology Meeting, Miami, November 15, 1973.

 

 

INVITED TALKS/PRESENTATIONS

"Topographical Location of Mitochondrial Respiratory Components", American Chemical Society Southwest Regional Meeting, Lubbock, TX Dec., 1984.

 

"Interaction of Hydrophobic Molecules with Heme Proteins", U.S. Air Force, Wright-Patterson AFB, October 29, 1984.

 

"Application of Fiber Optics to Hydrologic Measurements", Third Toxic Waste Technical Symposium, U.S. Geological Survey, Pensacola Beach, FL, March 24, 1987.

 

"Patents and Technology Transfer at the University", Oklahoma Business Incubator Association, June 10, 1993.

 

"Conflict of Interest" Workshop at 1996 Annual Meeting of Association of University Technology Managers, Charleston, SC February 11-14, 1996.

 

"Real-Time Reagentless Detection of CBW Agents". B.J. White and H.J. Harmon. Biodetection Technologies Workshop on Mobile Detection Lab at Biodetection Technologies Technological Responses to Biological Threats" Meeting, June 17-18, 2004, Washington DC.

 

"Reagentless Detection of CB Agents" to Water Contamination Emergencies: Enhancing our Response" June 2005, Manchester, UK.

 

"Real-Time Reagentless Agent and Analyte Detection and Identification". H.J. Harmon. Biodetection Technologies Technological Responses to Biological Threats" Meeting, June 9-10, 2005.Baltimore, MD.

 

"Optical Detection Using Protein and Enzyme Monlayers on Planar Waveguides" August 18, 2005. Biophotonic Workshop and Smart Fiber Optic Sensor Networks Workshop, Optoelectronics Industry Development Association, Rochester, NY.

 

"Optical Real-Time Detection Using Nanolayer Determinants" H. James Harmon and A. Oliver. Photonic Nanosystems 2005/MEMS & BioMEMS 2005: Biodetection Technologies- Sensing, Detection, Identification with Nanophotonics and MEMS. November 8, 2005, San Francisco, CA.

 

"Optical Detection of Chem-Bio Agents Using Monolayer Proteins and Enzymes on a Planar Waveguide" Bioterrorism Detection Technologies symposium at Pittcon 2006, Orlando, FL March 12-17, 2006.

 

"Optical Biodetection Using Biomimetic Receptors in Real-Time". H. James Harmon and Amanda Oliver. Biodetection Technologies- New Developments in Identification of Microrganisms and Chemicals. November 9,-10, 2006, San Diego, CA.

 

"Reagentless Real-Time Optical Biosensors Using Biomimetic Receptors" H. James Harmon and Amanda Oliver. First Biological Sampling ans Detection Symposium, April 30–May 1, 2007, Richmond, VA.

 

"Reagentless Real-Time Evanescent Optical Chem- and Biodetection Using Biomimetic Receptors and Ligands" 5th Annual Federal CBRN Detection Technologies Symposium "Emerging and Enabling Technologies for CBRN Detection", May 30 – June 1, 2007, Washington, DC.

 

 

EQUIPMENT HOUSED IN THIS LABORATORY

My laboratory houses state-of-the art optical spectroscopy capabilities including a CARY 4E dual beam spectrophotometer; a dual wavelength spectrophotometer for analyzing highly scattering samples; a single wavelength spectrophotometer for measuring kinetics at 30 microsecond resolution; an OLIS (On-Line Instruments) RSM-1000 rapid scanning spectrophotometer capable of recording fluorescence or absorbance spectra each millisecond or performing micro-second kinetics; Spex spectrofluorometer; lasers, light sources, monochromators, etc. Analytical chemistry equipment includes GC-MS, HPLC, and ion chromatographs. Each of the above instruments has a dedicated computer interface. Our 24-CPU parallel computing cluster is used for Quantum Mechanical Modeling. In addition, "general" chemistry and biochemistry/biophysics-type items are present- pH meters, oxygen electrodes, recorders, electrophoresis (DNA as well as SDS), balances, centrifuges, microfuge, etc.